Transdermal Therapeutic System

What are transdermal therapeutic systems?

Transdermal therapeutic systems are patches impregnated with a defined amount of an active ingredient. The active ingredient is released slowly and in a controlled manner through the skin and thus enters the patient's bloodstream. This transdermal route offers an alternative method to oral or intravenous administration of active ingredients.

How do transdermal therapeutic systems work?

The skin is a complex organ consisting of various layers. Transdermal therapeutic systems utilize the skin's ability to absorb certain molecules to transport the active ingredient into the body. The special composition of the patches ensures a controlled release of the active ingredient over a specific period.

What are the advantages of transdermal therapeutic systems?

Transdermal therapeutic systems offer several advantages over other administration methods. They enable a constant and controlled dosage of the active ingredient, which can lead to improved efficacy and tolerability of the medication. In addition, transdermal patches offer a convenient and discreet way of administration.

Another advantage of transdermal therapeutic systems is the bypassing of the first-pass effect, in which a part of the active ingredient is broken down by the liver during oral administration before it reaches the systemic circulation. Transdermal administration can avoid this effect, leading to more efficient drug absorption.

Summary

Transdermal therapeutic systems are an innovative and effective method of drug delivery that enables controlled and constant dosing of the active ingredient.